After the relative success of their debut album, Dope decided to record a follow up entitled Life. Several band changes had taken place once more; Tripp Eisen was fired from the group and joined Industrial metal band Static-X, so Virus, a guitarist/producer from New York City who was originally hired for bass, replaced him on guitar in 2000. Acey Slade was moved to the position of guitar, while Sloane Jentry (who had remained friends with the band) rejoined, this time on bass. On drums, Preston Nash was replaced by Racci "Sketchy" Shay.
The two singles from Life; "Now or Never" and "Slipping Away" reached No. 28 and No. 29 on the Mainstream Rock charts respectively. The album itself reached No. 180 on the Billboard charts and No. 6 on the Top Heatseekers, which up until that point was the band's highest charting. After the album's release, Simon Dope left the group to pursue a career as a video game producer.
"Debonaire" from the first album was used in the movie The Fast and the Furious. More soundtrack work was done by Dope in 2002, as the band recorded WWE chairman Vince McMahon's theme song "No Chance (In Hell)" for the WWE Forceable Entry audio release. Dope's music had previously been used as the background theme in ECW, and Rhino also used "Debonaire" as his entrance theme.
Around this period, Edsel Dope also had a public rivalry with the band Murderdolls, particularly vocalist Wednesday 13. An early version of that group had featured Racci Shay on drums; and under the name Murderdolls, it featured Tripp Eisen. Dope guitarist Acey Slade then left the band to join Murderdolls in mid-2002.
1.Take Your Best Shot
2.Now Or Never
5.Thanks For Nothing
6.Die MF Die
10.With Or Without You
13.March Of Hope